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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65241684cb265f1faad99bc2f1fa960d28532ce8bdfa9b8646fcd3de817ddd81' 
  AND token = 'b2IUKJTAf9AVN3JAxZDhVPhOI0vDHyOzWsc04cb2rm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}