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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b7d862b067375f2266bb3b92c5eaa470f2c321aa6779f1e60e30d72286b1e9' 
  AND token = '6gxebSHwL845lkElyTk7WiQa/5qGep//NKM9JSQaYzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}