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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53df3b4b77988ba9d1f19cc89d14b2fdc1ff7d5e8fff3bcd614c880bc932ad01' 
  AND token = '3e7aFOcrnSyHYtOyhQDiePOrvmazPfgeVnB4ezzE6iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}