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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2d4ba815844df542fba307eef16527f7f977f10541b9cc6725d58f0bb7c0d51' 
  AND token = 'a0mSIOwPdfI9FTvp+fW5jjrdVj2v63EjPBziHpeBQw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}