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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644356da96023f56f338e5233aabea6327e695f26cf1d2d28dfb7bc2cda5029f' 
  AND token = 'DeO1L6DRva9EGMLTC3ZONODNBYTINnq2pKgdEx6PKhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}