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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9201e4f2a62701b1e908000944d4947d0d3da63b2fdc39c01b4550e271a80452' 
  AND token = 'GeZ+OMPAiGaanmIO75N8xqNzTI1OMy3C2vQlVh3wWlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}