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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f53e8a4aebeee2fd59fa5d511cefc669ec2ab3e2217a5be7a384f1ecf648fbb3' 
  AND token = '48L7vnEGs+sjcOZzHDqkZdQFRbbRG3IZETYigWIdYok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}