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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a10b6a56088850d2b37c8ff05439f7fd8b103834a2343abe0e81c05721960c8f' 
  AND token = '1c9vCY/i6mw1+0GTfnLAdoQwES90O8A0szMUXOZuZmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}