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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6280589cf11c67b909c1ee8a0aee2e4aedcb8f2a012df34623f066ac54048e7c' 
  AND token = 'gMAlwzEB+K+iEf2gSEFPeM8MxMk2al0tfCSlidzgmKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}