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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b3276a6ea0d991f95a952e7cdefdbce2dd954069b5a40d74658690fc2a5cc5' 
  AND token = 'EKq6Xc1lHC+l0vbw+I/tfvT0Cx6T5on67fyKGtEXWsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}