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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '475d48d33055a7e08eb018f9afdfde3fe59d749be9717acd1dd3ba12451fdf74' 
  AND token = 'ljjHmbWpvG/e4hdhNEX+qf8bI9bcATFcQWEgRbj7xNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}