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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74e9cf978a9cc0689dec09433db0d942272035f02d8ac10d2a967bf9186d16af' 
  AND token = 'RNNvSliyXYLRJ3it1U1/cZdC8aA+A7WUlT7ZXFffqRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}