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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a53dcf11d461c42826350293826a54473bc31ddc5ac272e55164f41c8725c0e' 
  AND token = 'u1bnXVnTfUuHmuyyAi/L1m0dL8hQwK16s10DkfmOHmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}