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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '080fde2dba015f270c7e645207194b3820efa12d3e3a8467a7cce52f594a01d8' 
  AND token = 'pTY3aAzw6kgHCl7VLSS0vyg4ri83eEHZQoVcQycw000=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}