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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e01b25fbf58a4b6f250dcc698adeaa5c2f5af5804a6bbf930d13cdcdb616e6a' 
  AND token = 'qMz+NHjj3UkrljvZbnIc6r+C6wMm7BWMw8/CV0y2Ct0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}