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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '045e6af6ab6a7d6fc284e34ff6a3d45ec151f0724504211a3f7db9bb3abe542f' 
  AND token = 'IhVGYsSS1LMifSu6uDmQI+I191h7TgNB5PKlIDuo31c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}