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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0b0e86f122db30542e4cfaca1076da7592cfd8219c1b63650cc99dba8211c74' 
  AND token = '2SWPPA548yXBx22ZeCL78LKLo7AZkCNeRjz3UE2/2WY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}