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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d8a7e4a179e186d83fd66613921c3c8c564864662cb0f71dbc496c80d4b98a' 
  AND token = '0zA4NJHTma+lzgrLiEJJqa4i8rwpXm06M4y8KltHeRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}