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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db74ad97a6c3ee8830cc1a81d1aca19b4b1e05271ea6edb43484702b5a806f7' 
  AND token = 'EPkDkoTDFFB9Pm6lw1LBbAla0ey1vHp39Bj7Bn0+wjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}