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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3190be68b8071d0d4c13df06bacbed2b284cd50c5a081dd2b9f90062edc5d435' 
  AND token = 'ywWZ+DtKWgUPm5vM1EfY+CoDXz7fvrdbXX7SYPAqjHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}