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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e645a53003accad845995cce64acd2a5b4532b8ec56e53121c35d9949bcba9ce' 
  AND token = 'dEC7VL7DWhQHPVZ+xPMxET4PAyBuLuwCnFZSI2qEAKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}