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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73937f86721e43f9cab8d20afea02a01fb85dfc6f7abec131cc5a5db903afee2' 
  AND token = '86V4TzHjq+piZAlMTgjKwFH36aJ/jTMCCkcsx7osIE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}