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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44951a2b06b95158c417f35024243b7f2bcb1cc8a3f377858a244f7a8c4289fd' 
  AND token = 'hSYzVET9Et/pKt3D50Rx41htalO5GXHVyLLb1B+5RZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}