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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7bbe916bf0a114f7dd892a8e7f02fe70829d6d73e5b3b5873bb19eed10f9c37' 
  AND token = 'UDYY1dP6lO5Gd9OluaPOhwuJ88dT5vOAIL8ykfSQF/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}