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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37499ed2852f54b0fe12b248febdbab4ecf89ac7933c3763cd9288bba85b67dc' 
  AND token = '5ICWSWxz6NUXLeM2hW4E3X0HdUeEW0QiyFxriH5ag2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}