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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80adfb5291a511e99f1e1d879e3ad16de044fd8e1ee5c638da9089122a5aa7bb' 
  AND token = 'x6DNLPNeKhEB3h8Ma2zK4MoCdQoVw73WzbjbS6Z8B1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}