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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fb946e8ac2b618d0c624cb915f7b8bd0408588d90627fbcd780a433b2a2b0f3' 
  AND token = 'HAc2Qk8A9Gf2QEUQoxBzDYJfSDTQNNbOU7akz0ekfo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}