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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f292bdd6d71a5610d3d6ec5737d562820a45775da074b5d6c65136f39b7bfca' 
  AND token = '98sa+ZsUGdi5smBbWspzD/dvvYHqOYTnYblzXK80cOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}