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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '121c66624a10cf4b17bee44086e71468cc7415d91dae24b3f70fa7347ad4f58f' 
  AND token = 'E6YG00CMlflrZ1pgHOBdVVU5T4xdY9PTtx3L38Nhm/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}