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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ac022fe1350bb2aa2c9776201bf18e0ff064dae0b4c35a31ecde8a0d9350799' 
  AND token = 'c1nV4f3UG8urZ09LDCJ+twxW3ECxBv3ugTQXrDvS6Sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}