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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161e95cdca60ed487323307acaf543360b1ddf2148e7283c263dd4537b9fc4ed' 
  AND token = 'xcYO0ibsh1bbqYR4D/7jLGYbLqUZMAw21luyzWHk1OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}