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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca8bdea6ca5f479766e5d2b495f75d5c2d50b049f5449ff8e488e1817018f9c' 
  AND token = 'wJk3ypr5PDOwJ6FEyiqCYyd7AF3pVfIDtC55JcKdJrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}