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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4415c48a555f3ef7931423391b5d90fe514edb32f8ed6108223de06d71895de' 
  AND token = 'Anj/TN1VahrHL8VzDUj/yb4xyy1SWdi5TUa9Clk1V20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}