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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42710d01f699ae8a14f4592261400c26d2a3ee22bd3ffe4a17486e8c7ef1bb0' 
  AND token = '59366XesBQYDZXhj3pDV8itxuZhsVmcnk6u1+v7vVh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}