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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8047c5758b1426745f5a0c7d768f78847713a2eff5dfacdba614a50434e0170' 
  AND token = 'gNfkJ3cjPNlwcRf3AbG1XDYHLBYsiLX0zkr9qOaH0Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}