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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e9ce20aa8fdf11c433b6ec440eb99cf294295e6e76dd6320cd2a73c26e657f2' 
  AND token = 'BoM6FEuBqrEto7JLxxREiY4b1c1+VxtXBB1LTGc1Gl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}