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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1c5dc712c1a2c1dbfce27538e4b39861797b607010125ad3eb8773003cbe479' 
  AND token = '4YZ5JzHWfc+FAHUAO+lbRVdmoS8eRXf1Zl1QbEaJRds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}