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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456f7a172561adbe56f312b4933b6e5e22d23fbeba1114d7e386c989054f61cc' 
  AND token = '4uQ0alLpnt5XGmurV9eAwYrvKkkpuWoeQoRu9aYQXOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}