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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f1aea247fe159df744b7f032cfc354e922b544cb9120066f26d1a58d585b653' 
  AND token = 'Z5O/nnATh98Yf3C86F0nopUPr8MHqSe2VJ4Lr54yZlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}