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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '458f399870058e781c7c8b259ca622c68e031e0a31ca62a058bf92f356f98a54' 
  AND token = 'GMk9z5DAzTUcAF2Yqvxrmo/Jo8mnNzkaGlwC1fdoIDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}