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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6204a40a81d149718cccf74a2329beb5e76e7af1836a996746428e796d979d2' 
  AND token = 'oS2OJ4lzH9WX/Ixzm69BcXp0RcvszMwK5T10F+T4kBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}