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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44a1ec9539dfed5f22bf33c9d5a7c781e8ced7c33cf75314244c4bfb0a7544c5' 
  AND token = 'RR1yC5RVq/Cc7/bYc9rhsZ3wfKbV4U1UmFbAt/3W4a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}