SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25423a15a4b332264b2b7eda02ad5ff2ad819175da4365eb94d35ee5eb9d0da0' 
  AND token = '1Qb8ZHCtbSCyP0Le/spDu+KrHWcf195uXvqbD5Q+k4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}