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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2499c8996024fe04d0d8d9ff8409168ff5af7251f672795763500ea0069aa4d8' 
  AND token = 'xXO5saIGDCRLQmuyhSdwA8A2FEiIY6+GMZ6qwncOhZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}