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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f12d916f5bf11f863db24d4be4f0f91134be452f8bce2242dbb44ca7f286b1c' 
  AND token = 'GZ9PwlHxIeDfawlKMi/6vVX1lSsH4/LfL84V1UsLdYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}