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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae81c91141abf282465a4a0d5dc2efff645ba0d1535ebbb8cc48864a317e729a' 
  AND token = '+uXnPXeIGUDeudkxI0DsdQT9jm4XAPAhOxMiwvDALBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}