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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88f221c9a88fbc665cc7d00f8014054f2f10c3a4aed7359349fef8ec85a88ea4' 
  AND token = 'V+huD+ZZmTit4veHEjdXrD3eG4ai+ZPBmxEl0MOdfOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}