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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8dec2b8cbe64688145f7e4b0661eb0e5ae72e9781ef7e8bd45934d9200a121' 
  AND token = 'P/KcOM+p6rXKu0tAdwgcY0C6XNBbdihgqVaT8CQ6oPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}