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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3755a3afb7fb20a5e767b057bb112f5e882bf44e89be3ad9fed4c6122e14f493' 
  AND token = 'vIg8miE+b06kG6GOVd6ri6gcavJnNDUuBtifjPxIuvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}