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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cb7f361c5551bf95f91e134d064f293a859f29f2bc46ab67794b26ceb0dcb49' 
  AND token = 'RgNED4Wp3AUxUVORYmBB+O4SwS7vfJ6kmxOMqdbVCUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}